Background and Purpose: Proton arc therapy (PAT) is an emerging modality delivering continuously rotating proton beams.Current PAT planning approaches are time-consuming, making them unsuitable for online adaptation.This study proposes an accelerated workflow for adapting PAT plans.
Materials and Methods: The proposed workflow transfers spots from initial computed tomography (CT) to the CT of the day, updates energy layers considering the initial pattern, Bike Accessories - Computers and re-optimizes selected transferred spots based on their initial weights and impact on the objective function.A retrospective study was conducted on five head and neck patients who underwent plan adaptation on a repeated CT.PAT plans were generated with two different methods on the repeated CT: reference, created de novo, and smart-adapted, generated with the proposed adaptive workflow.
Robust optimization was performed for all plans.Results: Smart-adapted plans achieved similar mean dose to organs at risk as the reference: the largest median increase of mean dose was 1.9 Gy to the mandible; the median of maximum dose to spinal cord was 0.
5 Gy lower for the smart-adapted plans.The median target coverage, i.e.
D98, to primary tumor and nodes of smart-adapted plans decreased by 0.2 and 0.4 Gy for the nominal case, and 0.
4 and 0.6 Gy for the worst-case scenario; all smart-adapted plans met clinical objectives.The smart-adaptation Snap Caps method reduced average planning time from 19184 s to 5626 s, a 3.
4-fold improvement.Conclusions: Smart-adapted plans achieve similar plan quality to the reference method, while significantly reducing plan generation time for new patient anatomy.